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Showing posts from December, 2021

Manufacturing Methods for Production of Pharmaceutical Tablet

  A tablet is a pharmaceutical dosage form. It contains of a combination of active substances and excipients, generally in powder form, passed are compacted into a solid dose. Excipients: Diluents, binders or granulating agents, glidents and lubricants to ensure efficient tableting; Disintegrates: to promote tablet break up in the digestive tract; Sweeteners or flavours: to enhance the taste; Polymer coating: it is applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment. There are three methods by which  tablets  are manufactured; Wet granulation Dry granulation Direct compression Manufacturing process depends on many factors, including the compression properties of the therapeutic agents, the particle size of the therapeutic agent, excipients and the chemical stability of the therapeutic agent throughout the producing method. Wet Granulation It is most commonly used method for the man